Mesotherapy
Mesotherapy is a treatment that injects vitamins, minerals, enzymes and amino acids under the skin to support skin health. Derived from the words "meso" (middle) and "therapy" (treatment), this method acts on the middle layer of the skin, accelerating blood circulation and activating the immune system.
Creams and serums have difficulty penetrating the skin’s protective barrier; the necessary ingredients often fail to reach the target layer. Mesotherapy is a treatment that bypasses this barrier to deliver nourishing ingredients directly to the skin’s middle layer.
Mesotherapy, It is a medical aesthetic procedure in which personalized mixtures consisting of components such as vitamins, minerals, amino acids, and hyaluronic acid are injected into the middle layer of the skin (mesoderm) using very fine needles.
What Is Mesotherapy, and How Does It Work?
The effects of mesotherapy are based on two mechanisms. The first is mechanical stimulation: the tiny channels created in the skin by the micro-needles trigger the body’s repair process and promote the production of collagen and elastin.
Second, the pharmacological effect: the injected mixture delivers the building blocks the skin needs for regeneration directly to the target layer. The composition of the mixture is determined following an examination, based on skin type, needs, and the treatment goal.
The treatment can be applied not only to the face but also to the scalp. The goal of scalp mesotherapy is to directly nourish weakened hair follicles with vitamins, minerals, and amino acids.
For What Purposes Is Mesotherapy Performed?
Skin Rejuvenation
Restoring vitality and radiance to skin that has lost moisture and appears dull.
Hair Mesotherapy
Directly nourishing and strengthening the hair follicles to address hair loss.
Eye Contour
Helps reduce fine lines and a tired appearance around the eyes.
Neck and Decolletage
Supporting skin health in this area where signs of aging appear early.
Dark Spots and Uneven Skin Tone
Formulas containing brightening ingredients designed to even out skin tone.
Crack Appearance
Supporting the skin's healing process, especially for newly formed cracks.
Who Is It For?
The application is evaluated in the following cases
- People with dull skin, moisture loss, or signs of premature aging
- People who are experiencing hair loss or thinning hair
- For those who want to support their skin after seasonal wear and tear
- Those looking for protective and regular skincare
It does not apply or is postponed in the following situations
- Pregnancy and Breastfeeding
- Active skin infection in the treatment area
- Known allergy to any of the ingredients in the mixture
- Uncontrolled diabetes and certain chronic diseases — are assessed during the examination
How Does the Application Process Work?
Examination and Analysis
Skin type, needs, and goals are assessed; in hair treatments, the cause of hair loss is investigated.
Determination of the Mixture
The vitamin, mineral, amino acid, and hyaluronic acid content is tailored to individual needs.
Application
Microinjections are performed using very fine needles; the session lasts about 20–30 minutes.
Treatment Tracking
The intervals between sessions and the total number of sessions are updated by the physician based on the response.
How Many Sessions Are Needed, and When Will I See Results?
The approximate duration of a session; you can return to your daily routine after the procedure.
For skin treatments, a course of 4–6 sessions is typically planned, while for hair mesotherapy, a course of 6–10 sessions is planned.
The typical interval between sessions; maintenance sessions for the purpose of prevention are scheduled less frequently.
Frequently Asked Questions About Mesotherapy
Is mesotherapy painful?
Because very fine needles are used, most people describe the procedure as a slight pricking sensation. In sensitive areas, comfort can be enhanced by applying a topical anesthetic cream before the procedure.
How many mesotherapy sessions are needed?
For skin treatments, an initial course of 4–6 sessions is generally recommended, while for hair mesotherapy, an initial course of 6–10 sessions is recommended. In hair treatments, a noticeable difference is usually observed after the 3rd or 4th session; treatment courses are planned based on the individual’s response.
What should you be aware of after mesotherapy?
After the procedure, you may experience mild redness, sensitivity, or, rarely, small bruises; these usually subside within 24–48 hours. It is recommended that you avoid makeup on the first day and avoid saunas and intense sun exposure during the first few days.
Who is a good candidate for hair mesotherapy?
This treatment is recommended for women and men who notice thinning, loss of density, or increased hair loss. Determining the cause of hair loss is the first step in developing a treatment plan; in cases of genetic hair loss, maintenance sessions are required to preserve the current condition.
In which season is mesotherapy performed?
The procedure can be performed in any season; using sunscreen after the procedure is important at all times. Provided that intense sun exposure is avoided during the summer months, there are no obstacles to scheduling the procedure.
Can mesotherapy be combined with other treatments?
Yes; mesotherapy, which supports skin health, Hydrafacial They can be scheduled in different sessions within the same treatment plan, such as skincare treatments or injection treatments. The doctor decides on the order and timing.
This content was prepared by Dr. Melis Ülger, who works in the field of medical aesthetics, and has been reviewed for medical accuracy. Get information about the doctor.
Last updated: July 2026 · Caddebostan, Kadıköy / IstanbulRelated Applications
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Information Guide
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Detailed guides prepared by Dr. Melis Ülger.
- Reviews of Those Who Have Mesotherapy: Before and After Experiences
- How Many Sessions Should Mesotherapy Be Applied? Treatment Planning Guide
- Kadikoy Hair Mesotherapy
- Get Rid of Skin Blemishes with Spot Mesotherapy
- Use of Mesotherapy in Stretch Mark Treatment: Repair Support for Your Skin
- Under Eye Mesotherapy: Goodbye to Bruises and Bags
- Before and After Mesotherapy: 2026 Results and Process
- Under-Eye Mesotherapy: The 2026 Guide to Dark Circles and Radiance








