Salmon DNA Vaccine

The salmon DNA vaccine is a mesotherapy treatment that aims to support the skin’s repair and regeneration process by administering purified polynucleotides (PDRN) derived from salmon into the skin via microinjections.

The unseen aspect of skin aging is the slowing of its regenerative capacity. The salmon DNA treatment is a rejuvenation procedure that aims to support this capacity through microinjections containing polynucleotides.

Salmon DNA The PDRN vaccine is a mesotherapy treatment that aims to support the skin’s repair and regeneration process by administering purified polynucleotides (PDRN) derived from salmon into the skin via microinjections.

The Salmon DNA Vaccine Application, by Dr. Melis Ülger
About the App

What Is the Salmon DNA Vaccine, and How Does It Work?

The main component of the product is polynucleotides (PDRN): DNA fragments derived from salmon and purified to ensure high compatibility with human tissue. This compound provides the building blocks that cells can use in their repair processes.

The treatment aims to support fibroblast activity and microcirculation in the skin; the goal is to achieve a gradual improvement in elasticity, hydration, and skin texture over the course of the treatment.

What sets it apart from traditional vitamin blends is that its ingredients are specifically targeted at the repair mechanism; when necessary, the two approaches can be combined within the same plan. For the general framework of the method, our mesotherapy page You can review it.

A healthy-looking complexion after skincare
The product consists of purified polynucleotides (PDRN).
Target Audience

What Does the Salmon DNA Vaccine Target?

Elasticity

Skin Quality

Supporting skin tissue quality in skin that has lost its elasticity.

Humidity

Deep Moisture Support

Supporting the skin's ability to retain moisture from within.

Periorbital

Eye Contour

A sensitive area where fine lines and a tired appearance are accentuated.

Repair

Fine Lines

Smoothing the appearance of fine lines through the renewal process.

Skar

Acne Scar Support

Supporting the track view through the repair mechanism.

Neck & Decolletage

Neck and Decolletage

Supporting areas showing signs of premature aging.

Evaluation

Who Is It For?

The application is evaluated in the following cases

  • People who show signs of loss of skin elasticity and fatigue
  • People who are bothered by fine lines around their eyes
  • Those experiencing moisture loss and a dull appearance
  • For those looking for a protective and restorative skincare investment

It does not apply or is postponed in the following situations

  • Pregnancy and Breastfeeding
  • Active infection in the treatment area
  • History of allergy to fish-derived foods — assessed during the examination
  • Some chronic conditions — treatment plans are developed based on the patient's medical history
Step by Step

How Does the Application Process Work?

01

Skin Analysis

Skin quality, elasticity, and goals are assessed.

02

Preparation

The skin is cleaned; a topical anesthetic cream may be applied for comfort.

03

Application

The product is administered into the skin via microinjections; the session lasts 20–30 minutes.

04

Treatment Tracking

Sessions are scheduled every 2–3 weeks; the maintenance regimen is determined based on the response.

Effect and Duration

How Many Sessions Are Needed, and When Will I See Results?

3–4 sessions

An initial treatment course, typically scheduled at 2- to 3-week intervals.

20–30 min

The approximate duration of a session; you can return to your daily routine the same day.

Gradual

Because the repair process takes time, the effects become more noticeable as the treatment progresses.

Frequently Asked Questions

Frequently Asked Questions About the Salmon DNA Vaccine

Is the salmon DNA vaccine safe?

The polynucleotides in the product are purified to ensure compatibility with human tissue and are free of allergenic proteins. The decision to administer the treatment is made in each case following a physical examination and review of the patient’s medical history.

I'm allergic to fish. Can I still get this done?

Even if the product has been purified, a history of allergy to fish-derived products must be disclosed during the examination; the decision to administer the product is made based on this assessment.

What is the difference between this and classic mesotherapy?

Classic mesotherapy provides nutritional support focused on vitamins and minerals, while salmon DNA directly targets the skin’s repair mechanisms. The two approaches can be combined in the same treatment plan as needed.

How many sessions are needed?

A course of 3–4 sessions is generally recommended at intervals of 2–3 weeks; maintenance sessions may be scheduled to preserve the results achieved. The number of sessions is adjusted based on the skin’s response.

What should you keep in mind after the procedure?

There may be slight redness on the skin and small bumps at the injection sites; these usually subside within 24–48 hours. It is recommended to avoid makeup on the first day, and to avoid saunas and intense sun exposure for a few days.

At what age can it be done?

There is no specific age requirement; treatment can be considered once signs of loss of elasticity and skin aging begin to appear. Planning for preventive care is also done during the examination.

Dr. Melis Ulger
Dr. Melis Ulger

This content was prepared by Dr. Melis Ülger, who works in the field of medical aesthetics, and has been reviewed for medical accuracy. Get information about the doctor.

Last updated: July 2026 · Caddebostan, Kadıköy / Istanbul
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